Which disease is screened for in blood donors primarily through questions during the screening process?

The screening of blood donors primarily involves asking specific questions about travel history, lifestyle, and potential exposure to infectious diseases. Malaria is a disease of particular concern during blood donation screening, especially due to its transmission through blood and its occurrence in various regions of the world.

When donors have traveled to regions where malaria is endemic or if they have had direct exposure to certain at-risk populations, they are often asked detailed questions about their health and recent activities. This approach helps identify potential cases where a donor may have been exposed to malaria, which is crucial since the disease can persist in the blood without obvious symptoms.

While HIV, Hepatitis C, and Syphilis are also significant, they typically involve both questionnaire screening and laboratory testing of donated blood for detection. The emphasis on travel and risk factors for malaria during the screening process distinguishes it, showcasing how careful questioning can help ensure the safety of the blood supply.